– A new mechanism of cancer immunotherapy have been developed by a team of Stanford ChEM-H, which says, by removing certain sugars from the cancer cells surface, those cells become visible to the immune system, and hence they become recognizable by innate immune cells, thereby increasing the chances of getting attacked by them.
It was a well-known fact that if certain sugars molecules are present on cancer cells surface, it is less likely that it will respond well to drugs and therapies. But owing to the less number of researches being carried out in this domain, the exact function of these halo sugars (glycocalyx) was unknown.
Evidence reveal that amongst the few labs that do study the glycocalyx, including Bertozzi’s, have found that sialic acids, a subset of sugars, acts as a signal for the innate immune system to neglect the otherwise harmful appearing tumor. Elimination of those set of sugars, may enhance the ability of innate immune to recognize and attack the cancer cells.
The tests were conducted and prospective results came to be true!
This new research is going to revolutionize the mechanism of action of immuno therapeutic drugs, thus creating wide range of opportunities for innovation and development in this field. Our researches will help explore the latest trends, developments, opportunities and potential threats for immuno therapeutic drugs market.